key role of serine in glutathione transferase functions Metabolism Health and Disease and as a Conditionally Essential Amino Acid Glutathione transferases: substrates, inihibitors and

Dysregulation of KATs, KDACs, and bromodomain-containing proteins plays a role in aging and pathogenesis of cancer and neurodegenerative diseases, such as Parkinsons disease [47,48]

Calverley reports funding from the Medical Research Council, EU HORIZON 2020 programme, Wellcome Trust, GSK, Boehringer Ingelheim and Novartis

30-Second Takeaway Supplementing with glutathione, an antioxidant that neutralizes free radicals, is generally safe

Apoptosis in arsenic trioxide-treated Calu-6 lung cells is correlated with the depletion of GSH levels rather than the changes of ROS levels

Mechanistic enzymology in drug discovery: a fresh perspective