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Oral B12 Supplements: A Convenient Alternative Oral B12 supplements can also provide valuable health benefits, but they tend to be less effective than injections

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As well, some people may have allergies or medical conditions that do not allow them to be a good candidate to receive vitamin B12 shots, such as kidney problems, low potassium levels, deficiencies in other vitamins such as iron or folic acid, or just an allergy or sensitivity to vitamin B12 itself