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revealed that the transcript of BCAT 1 is positively regulated by the oncogenic RNA binding protein Musashi 2 (MSI2), which promotes the production of BCAA in leukemia cells and the development of the disease (Fig

Moreover, mRNA editing and alternative splicing of the different NMDA subunit genes confer more complex properties to the NMDA receptors conformation, which have been extensively reviewed by Hansen and colleagues (Hansen et al., 2021)

Metabolomic analyses of cerebrospinal fluid (CSF) from drug-resistant epilepsy patients show alterations in oxidative stress markers (e.g., lipid peroxidation products), suggesting possible ferroptotic activity (73, 74)

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Participants with hepatic impairment were allocated into three groups, with the degree of impairment categorised by the investigator according to ChildPugh criteria: mild (Grade A