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Description
What is supported in animal models Increased lipolysis, increased fat oxidation, decreased lipogenesis, no apparent effect on plasma glucose or insulin sensitivity, and signal that intact beta-3 adrenergic receptor activity matters for the fat-loss effect
The three pathways work in concert rather than competition
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PEGylation helps extend the circulation time of nanoparticles through the enhanced permeability and retention (EPR) effect
