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Although treatment was well tolerated, only a subset of patients derived a therapeutic benefit 15,16 indicating that the reprogramming of the TME will be essential for the efficacy of immune-based therapies

Produces a depletion of releasable neuronal monoamine neurotransmitters Similar mechanism as deutetrabenazine (Austedo )

doi: 10.1111/pai.12965 50 KleniewskaPPawliczakR

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