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In vitro studies of the hemoglobin auto-oxidation revealed that the reaction is slow ( k = 0.0115 h 1 ) under normoxic conditions (Nagababu et al., 2002), but is facilitated dramatically upon partial deoxygenation (Abugo and Rifkind, 2 of 1.33 kPa (Rifkind et al., 2004)
