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This suggests that the demyelination occurring due to LPC treatment is associated with astrocyte activation, similar to what is proposed to occur in vivo (Yoon et al., 2017)

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The use of GsMTx4 before mechanical stimulation of the Piezo1 ion channel produced almost 100% inhibition, which suggested that the change in membrane properties near the channel was accompanied by the closure of the Piezo1 channel (Bae et al., 2011)
Cancer 21 (1), 132