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The meta-analysis data on L-carnitine showed an average weight reduction of 1.21 to 1.33 kg compared to placebo groups, according to studies published in Clinical Nutrition ESPEN and Obesity Reviews

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Carnitine: L-Carnitine is an amino acid that plays an essential role in energy production and optimal mitochondrial function
doi: 10.3390/ijms18061316

Subcutaneous fat in the limbs has lower beta-3 density and higher alpha-2 adrenergic receptor expression, which is anti-lipolytic