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Unregulated clinics may lack these safeguards

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Figure 1 It is fundamental to underline again that the beneficial therapeutic effects of O 2 -O 3 therapy are based on the ozone ability to act through a hormetic doseresponse mechanism, being able to promote the generation of biochemical mediators capable of inducing beneficial mild oxidative stress effects ( 2 -O 3 window (Travagli et al., 2007), is elicited by the production of controlled low doses of ROS mainly acting as signaling molecules and boosting the formation of LOPs

Distribution of radio-labeled N-Acetyl-L-Cysteine in Sprague-Dawley rats and its effect on glutathione metabolism following single and repeat dosing by oral gavage
