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It was very very hard to achieve anything prior to the Methyl-B12 as I only had a partially-functional-brain for ~21 years and then I only had half-a-brain for the last 2 years on the keto, in which I used my restored half-a-brain capabilities to read and research medicine to figure out to test myself for the Transcobalamin

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Now as for plain lipo I cant answer for that

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In fact, the expression of those genes was lowered to levels similar to those of acne patients. So it looks like by intaking extra vitamin B12, we could be prompting the bacteria in our skin to slow down on their production of it, which leads to an imbalance that could heighten our risk of developing acne