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PD-1+ and TIGIT+ Tregs migrate to sites of inflammation in a chemokine receptor-dependent manner, with CCR6 and CCR7 playing pivotal roles in their tissue homing

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For adults, the cutoff for serum holoTC, based on the relation of holoTC to serum methylmalonic acid, is 12 mol/L), the association of total serum B12 levels with serum MMA (and tHcy) was explored with restricted cubic splines (Figure 22b.5)