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22 Therefore, to determine whether the metabolite induces proteotoxicity in part through UPS inhibition, we reduced proteasome function with a range of MG132 concentrations and identified that (at concentrations above 5 M) MG132 induces neurodegeneration in the presence of -synuclein and that this neurotoxicity epistatically regulates metabolite-induced neurotoxicity (Supplementary Figure S4a)

Instead, NAC is used to provide cysteine in a stable supplement form

doi: 10.1016/j.nutres.2012.12.010

Nrf2 is the key transcription factor required for activation of ARE

You can relax, read, or use your phone during the treatment