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A specific type of TRx (f-type) has been shown to be glutathionylated on a cysteine residue away from its active site, resulting in a decreased activity towards specific target proteins including NADP-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [189]

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Alpha Arbutin and Beta Arbutin The inclusion of alpha and beta arbutin in the formula adds to the creams skin-lightening effects