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HSCs can be activated by hepatocytes with cellular damage and can simultaneously increase synthesis of collagenase inhibitors, and activate Kupffer cells and neutrophils
and nutrition and clinical medicine can translate these findings into implementable dietary recommendations or complementary therapeutic programs, which can then be verified in clinical trials

PRDX6, while predominantly cytosolic, is also localized to lysosomes and acid organelles 111,112

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Male partners should also be tested for MTHFR, as this mutation can affect not only sperm morphology and DNA quality but contribute to oligo-asthenospermia
