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Description
This problem could be partly solved by the addition of reducing agents, such as antioxidant glutathione and exogenous astaxanthin, which could ameliorate excessive oxidative stress and help to maintain a high -PL formation rate during the fermentation (Yan et al., 2018
It is a tightly regulated reaction that depends on both the availability of the amino acids (cysteine, glycine, and glutamate) and the rate-limiting enzyme, glutamate-cysteine ligase ( GCL )

On the other hand, higher levels of glutathione reduced the oxidative stress in cancer cells

The practical result can include temporary increased fine lines, mild sagging, or a "tired" appearance

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81
