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Description
Some variants have clear structural explanations for their loss-of-function, for example, variants can disrupt binding of carnitine (R471C/H/P), affect the Na + -binding site (N32S), disrupt the TM2-TM11 H-bonding network (S467C) or perturb gating residues conserved in OCTs/OATs (R169Q/P/W)
To understand the independent and interdependent roles of TG hydrolysis and fatty acid oxidation, we generated mice with a liver-specific KO of Atgl, the first step in TG hydrolysis (Atgl L/ )

Hu, 2007

14, e202100175

Revista Peruana de Medicina Experimental y Salud Publica, Vol
