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Morelli M, Carta AR, Kachroo A, Schwarzschild MA (2010)

Systematic reviews of oral vitamin B12 therapy in vitamin B12 deficiency The first evidence-based analysis by the Vitamin B12 Cochrane Group in 2005 supports the efficacy of oral vitamin B12 as a curative treatment, with a dose between 1,000 and 2,000 g (1 and 2 mg) initially prescribed daily and then weekly [27]

today it is used off-label through compounding and stimulates GH with a more physiologic pulsatile pattern

[DOI] [PubMed] [Google Scholar] 84.Raghavan R, Fallin MD, Wang X

The intracellular concentration of GSH is in the millimolar range, and the extracellular concentration is in the micromolar range
