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Overall, in biological systems, these antioxidant enzymes play essential role in defending against harmful reactive oxygen species (ROS) and free radical [63]

doi: 10.1007/s12311-013-0511-x 100 LaiM

Paoli A, Bianco A, Damiani E, Bosco G

It tackles severe deficiency symptoms

Although numerous preclinical studies have demonstrated significant therapeutic potential of targeting ferroptosis pathwayssuch as using iron chelators, modulating GPX4 activity, or inhibiting lipid peroxidationrecent clinical trial results indicate that strategies aiming solely to reduce iron accumulation may have limited efficacy in clinical practice