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This interaction leads to ligand-independent activation of ER
The search for novel metallodrugs or metal complexes that target cancers is still a field of high interest in the pharmaceutical sector
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An in vitro study of human bronchial epithelial cells from patients with COPD or asthma showed that increased oxidant burden may lead to reduced corticosteroid responsiveness in airway epithelium, with important consequences for the integrity of the epithelial barrier and associated production of pro-inflammatory cytokines [43]
