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When these signals are sensed, oligomerization of inflammasomes occurs, particularly the NLRP3 inflammasome (Nucleotide-Binding Oligomerization Domain-like Receptor Family, Pyrin Domain-Containing 3), which recruits the adaptor protein ASC and leads to activation of caspase-1 and subsequent pyroptosis (Pachathundikandi et al., 2020)

The Indian colony samples were divided into two groups based on their origin (Walter Reid or laboratory-reared strains)

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Mass photometry analysis was compatible with a shelterin complex of a molecular weight around 700 kDa and a subunit stoichiometry of 4:4:2:1:1:1 for TRF2:RAP1:TRF1:TIN2:TPP1:POT1

doi: 10.1038/s41467-021-23499-w 274 MeuerSEckerUHaddingUBitter-SuermannD