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It is a single polypeptide chain amino acid with 70 residues, and its major site for its production is the liver

Mar 2015;239(1):21-30

IL, iNOS, inducible nitric oxide synthase

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AGA: androgenetic alopecia DHT: dihydrotestosterone AR: androgen receptor DPCs : dermal papilla cells DSCs : dermal sheath cells miRNAs: microRNAs IGF-1: insulin-like growth factor 1 qPCR : quantitative PCR AGA-O: AGA occipital hair follicle AGA-F: AGA frontal hair follicle Normal-F: frontal hair follicle of normal subject siRNA: small-interfering RNAs HE: Hematoxylin and Eosin ChIP: chromatin immunoprecipitation ORS: outer root sheath HF-KCs: hair follicle keratinocytes IHC: immunohistochemistry The authors thank Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering for providing experimental instruments