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Manifests itself in the form of swelling and bluish to black skin discoloration

Following a series of processes, free cholesterol absorbed by NPC1L1 is esterified and transported as chylomicrons into circulation, ultimately being assimilated by the liver [14, 15]

3,24 Survival with favorable neurologic outcome can be achieved with suitable treatment

The fluorescence intensity of those pixels was weak compared to high-concentration Nile Red staining (Supplementary Figure S3), although some small lipid particles can be still observed in the gonad region (some of which are indicated by yellow arrowheads in Figure 3F)