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Hexarelin does this through a calcium/PKC cascade while blunting somatostatin's inhibitory signal, and Ipamorelin is considered more selective because it does not meaningfully raise cortisol or prolactin alongside GH

Enteroendocrine cells produce hormones regulating secretion of digestive enzymes and insulin, peristalsis of the intestine, satiety, and immune response (Jung et al., 2010)

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