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Patients should promptly report any adverse reactions or discomfort following an injection using bacteriostatic water

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For people considering switching from tirzepatide to semaglutide or vice versa, the decision should be based on efficacy, tolerability, cost, and availability rather than on the B12 additive, since both compounds have B12-containing versions with the same potential concerns

Gradual dose reduction over 8-12 weeks may help transition to weight maintenance without medication

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