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Furthermore, our single-cell mass cytometry approach was limited to ~40 proteins, capping the number of metabolic pathways we could interrogate simultaneously

5.1.3 Tocopherols (vitamin E) Tocopherols are lipid-soluble antioxidants essential for membrane integrity synthesized in the plastid envelope from homogentisic acid and isopentenyl diphosphate

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Using RNA interference strategies Blanger and collaborators observed that a similar decrease in Glo-1 activity (80%) does not impact astrocytic and neuronal cell viability to the same extent using primary mouse cortical cultures as a model (Blanger et al., 2006b)