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Among various alkylating agents, N-ethylmaleimide is identified as the most reliable for thiol stabilization in liquid chromatographymass spectrometry (LC-MS) workflows, while specific reagents such as monobromobimane or -(4-hydroxyphenyl)ethyl iodoacetamide (HPE-IAM) are required for persulfide and polysulfide detection
Background Patients with myalgic encephalomyelitis (ME, also called chronic fatigue syndrome) may respond most favorably to frequent vitamin B12 injections, in vital combination with oral folic acid
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