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The initiator of the pathophysiological process has not been elucidated yet, although acute gastrointestinal infections have been found to initiate the symptoms in a certain group of patients with IBS (post-infectious IBS) (81)

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Wang J, Feng Y, Wang Y, Xiang D, Zhang X, Yuan F (2017) Autophagy regulates Endothelial-Mesenchymal transition by decreasing the phosphorylation level of Smad3

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
