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Together these results illuminate an evolutionary conserved pathway that links low cellular thiols to the activation of the ER stress response and geroprotection

In addition, FTD3 neurons recapitulate glucose hypometabolism observed in FTD patient brains

We also applied scaling to the NAD pool and synaptic glutamate release, which were literature-driven but had to be approximated, as we did not find exact numbers for their changes with aging

Nishimura, Yasushi & Kuroda, Motonaka, "Candida utilis containing gamma -glutamylcysteine", published 2004-12-22, assigned to Ajinomoto KK EP 1452585, Nishiuchi, Hiroaki

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