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Unlike a pure cell culture (where individual cells grow in a dish), ex vivo organ culture preserves the complete tissue structure in this case, whole hair follicles with all their cell types intact

Consequently, we observed that this beneficial effect, after direct injury (permanent ligation) applied to one or two major vessels, could instantly oppose more general damage (maintained intra-abdominal hypertension, either high (grade III) or very high (grade IV)), as all blood vessels which can be compressed with increased intra-abdominal pressure

(2010) used the MCL transection model specifically

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The peptide is naturally produced by the body, which suggests a favorable safety profile, but exogenous administration at supraphysiological doses may carry unknown risks