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Additionally, repeated cocaine administration for six days (50 mg/kg, i.p.) increased putrescine levels in six brain regions, including the striatum, hippocampus, and cortex, which returned to normal levels after three days of withdrawal 51

Edmund, Schmidt, Nathalie

In addition, it has been shown that IgA-deficient mice exhibited persistent intestinal colonization of Proteobacteria , which, in turn, led to permanent intestinal inflammation and increased susceptibility to neonatal and adult models of intestinal damage [87,88]

J Clin Gastroenterol 51(6):500507
