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Description
The peptide completed six randomized, double-blind, placebo-controlled clinical trials involving over 900 participants, establishing excellent safety and tolerability

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Progressive reduction in body weight after treatment with the amylin analog pramlintide in obese subjects a phase 2, randomized, placebo-controlled, dose-escalation study

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Its mechanism is competitive inhibition within the NNMT catalytic pocket, blocking the methyl transfer from SAM to nicotinamide
