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Fedets OM, Dmytruk KV, Adaszek L, Kurlyak IM, Dmytruk OV, Lisiecka U, et al

[DOI] [PubMed] [Google Scholar] 90.Wang R., Jiao H., Zhao J., Wang X., Lin H

4-( N -( S -glutathionylacetyl)amino)phenylarsonous acid is a prospective cancer drug and has just completed a phase I dose escalation study in patients with solid tumors refractory to standard therapy ( 4-( N -( S -glutathionylacetyl)amino)phenylarsonous acid consists of a phenylarsenoxide moiety attached by an N -acetyl linker to the cysteine thiol of reduced GSH ( Figure 3 )

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It has been shown that oxaliplatin, like other platinum compounds, spontaneously interacts with thiols under cell-free and in-cellulo conditions 25