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Most patients adapt quickly, but about 5% find it prohibitively complicated

Poultry Science, 103(1), 103257

doi: 10.1104/pp.104.055566 79 Nunes-NesiA.SulpiceR.GibonY.FernieA

We hypothesized that age-dependent elevation of labile iron, coupled with a reduction of glutathione levels conspire to lower the threshold for ferroptotic signaling, increasing the vulnerability of aged animals and implying that disruption to the iron-glutathione axis is fundamental to natural aging and death

Such vials are common because theyre cheap, but try to use single-use B12 ampules or tightly sealed B12 vials
