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According to a study published in PubMed Central (NIH), IV administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency

10.1016/j.lfs.2021.120036 54 GhoshS.BasakP.DuttaS.ChowdhuryS.SilP

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Additionally, compounded drugs serve as alternatives when certain medications are not available due to manufacturing issues or discontinuation