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While emerging technologies, such as asymmetrical flow field-flow fractionation 20 , tangential flow filtration 21 , electrochemical fluidic stimulation 22 and double-coupled harmonic oscillation (that is, EXODUS) 23 could also serve as appealing alternatives (Supplementary Discussion), it is notable that all conventional and contemporary EV isolations require preprocessing of samples, such as serial centrifugation and microfiltration

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The standard starting dose is 0.2 mg per night, injected subcutaneously