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according to the latest meta-analysis including over 11 million patients, the rate for the world population is 1 : 313, but in patients with ischaemic heart disease the incidence is 10 times higher (1 : 31), with premature ischaemic heart disease 20 times (1 : 15), and in those with severe hypercholesterolaemia, 23 times higher (1 : 14) [276]

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doi: 10.1038/mp.2010.88 59 AfonsoPDe LucaPCarvalhoRSCortesLPinheiroPOliveirosBet al

Enhancement of vitamin C-induced myogenesis by inhibition of extracellular signal-regulated kinase (ERK) 1/2 pathway

doi: 10.7759/cureus.14722