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Economies of scale may be limited for peptide drugs treating rare conditions, where small patient populations cannot support large-scale manufacturing investments

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Because of these properties, it is commonly discussed in relation to issues such as leaky gut, IBS, stomach ulcers, and other digestive concerns

As expected, DARA treatment reduced CD38 expression on BM-localized MM cells as well as on monocytes, B cells, T cells and NK cells, compared with baseline ( Supplementary Figure S1 )

Chronic, uninterrupted activation can lead to pathway desensitization, the biological equivalent of diminishing returns