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Their activation near the blood-brain barrier, in the perivascular space, can increase vascular permeability and prime microglia, the resident immune cells of the central nervous system 21

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doi: 10.1016/j.biopha.2005.01.004

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Here, the pretreatment with aqueous extract of Ab modulated the systemic and local release of proinflammatory cytokines, inhibited the leukocyte infiltration into peritoneal cavity, increased phagocytosis and NO production in infectious focus, leading to complete inhibition of bacterial burden in blood and peritoneal cavity
