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The role of autophagy and mitophagy in the heart Given the unique physiology and limited regenerative capacity of cardiomyocytes, autophagy and its mitochondria-selective subtype, mitophagy, collectively emerge as two of the most vital mechanisms for maintaining cardiac proteostasis and long-term myocardial health

(60) found that a high-sodium diet influences the accumulation of A peptide, exacerbates cognitive decline, and increases the propensity to AD

Underlying both patterns is the progressive functional exhaustion of tumor-specific T cells, which reflects a dynamic equilibrium between immune attack and tumor evasion, a balance that is continuously challenged within an immunosuppressive tumor microenvironment (TME) sculpted by immunoediting

[21] Dietary interventions and modifications shown to downregulate IGF-1 activity, such as vegan diets, have been associated with a lower risk of cancer

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