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In conclusion, the p53-MDM2 axis represents an important target in cancer therapy, and natural products offer a valuable reservoir of bioactive compounds for therapeutic intervention

Abstract Oxidative stress is recognized as both a causative and contributing factor in many human diseases

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Based on this, in the subsequent I/R- and TMT-induced myocardial injury model, the drug not only enhanced GSH levels and GPX and GST activities to lower oxidative damage but also reduced TMT-induced pyroptosis and I/R-mediated apoptosis [205,206,207]

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