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In the body, glutathione exists in both thiol-reduced (GSH) and disulfide-oxidized (glutathione disulfide

While arsenate does not inhibit any of the enzymes of glycolysis, it dissipates the redox energy available from the GAPDH reaction and prevents the formation of ATP by substrate-level phosphorylation at the PGK reaction

There is a high comorbidity between the anxiety disorders and MDD (Bobo et al., 2022)

Tsvetkov AS, Arrasate M, Barmada S et al (2013) Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration

M., Howe, S