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However, the body is generally very efficient at excreting excess B12 through urine without any issues

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Clin Sci 122:253270 Balapattabi K, Bannuru RR, Elsayed NA et al (2025) Introduction and methodology: Standards of care in diabetes2025

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The guidance around the management of B12 deficiency in people treated with metformin is a little unclear, owing to a lack of clinical evidence in this area

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This misconception is reinforced by NICE Guidelines despite the wealth of journals stating the opposite

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The answer is, absolutely not

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