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PMID: 34418768

Its primary mechanisms include the inhibition of pathological TGF- signaling, suppression of cell proliferation, promotion of apoptosis, and attenuation of inflammatory responses, thereby reversing vascular remodeling [7]

The AUC at 100 mg/kg/day in pregnant rats was approximately 2 times the AUC in patients at 100 mg approximately every 12 hours

Effect of PTMS on phase separation IRD-containing ALS-associated proteins can be highly modified through PTMs because they are easily exposed to the external environment owing to a lack of secondary structure 41

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