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Data availability The raw data used for systematic review data analysis and input to our models are available at Figshare 87 ( and Code Ocean ( Data identified in our systematic review are also available for download or to view and visualize in our interactive data repository ( The static maps in Fig

Signs and symptoms of vitamin B12 deficiency can include fatigue, pale skin, headaches, shortness of breath, fast heartbeat, gastrointestinal issues, mouth inflammation, paresthesias (abnormal sensations), decreased cognitive ability, depression, muscle weakness, imbalance and incoordination, vision problems, and erectile dysfunction