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After four weeks, those treated with Pycnogenol, at dosages of either 150 mg or 100 mg daily, had increased cochlear blood flow in the affected ear and reduced tinnitus severity, and the effects were more pronounced in those receiving the higher dosage

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Initial response at 4 to 8 weeks

In Temperature: its measurement and control in science and industry

422 Two large cross-sectional studies using detailed QST profiling found greater thermal insensitivity in painful than painless DPN, suggesting more advanced small fiber dysfunction