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This review highlights recent advances in unraveling the circuitry of the ENS and its diverse functions, the mechanisms by which local factors modulate its activity, and revisits some longstanding questions that remain to be addressed

Emerging research explores applications in spinal cord injury repair, stroke recovery mechanisms, and protection against neurodegenerative processes

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The binding of Na + appears to foster the interaction of GIRK channels with phosphatidylinositol 4,5bisphosphate (PIP 2 ), which is required for channel activation (Ho and Murrell-Lagnado, 1999