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Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination

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Some compounds that showed synergistic effects along with ciprofloxacin include Indirubin, Capsaicin, Silybin, and Kaempferol 88,89,90,91

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Activation of cannabinoid receptors (particularly CB1 receptors) in the hypothalamus and testis can inhibit GnRH release and reduce LH and FSH secretion, thereby impairing steroidogenesis and sperm production