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We determined the level of intracellular ROS by measuring the oxidation of DCFH-DA

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In another study, ectonucleoside triphosphate diphosphohydrolase-1 (ENTPD1) was upregulated in AraC resistant AML which was associated with enhanced mitochondrial activity ( 3.1 Therapy-induced adaptations in TCA cycle proteins and metabolites Although Otto Warburg found that cancer cells may rely on glycolysis rather than oxphos for their energetic needs, studies in more recent years have found that certain cancers may preferentially utilize oxphos rather than glycolysis

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Hormonal activation of a kinase cascade localized at the mitochondria is required for StAR protein activity