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Melatonin may exert anti-inflammatory effects at both the cellular and molecular levels

The details of the mechanism by which this occurs is poorly understood at a molecular level, however as mentioned above, it is largely facilitated through export of GSH conjugates of the targets [69]

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This approach highlights gene therapies versatility in upregulating and downregulating key pathways involved in liver disease progression (Kyritsi et al., 2020)

This consideration explains why, under excess H 2 O 2 , cells with an initially higher GSH concentration display a faster GSH oxidation
