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Within these exploration tasks, it is one more indication that exercise is a valid precision lifestyle intervention to optimize neuroplasticity [202]

Curcumin increases anti-oxidant protection by improving strength and physical performance in elderly subjects, potentially preventing the onset of sarcopenia and blocking the progression of proinflammatory signaling [164]
DNMT1 is the primary maintenance methyltransferase and preferentially methylates hemi-methylated DNA during replication, ensuring that methylation patterns are preserved in daughter cells

Nrf2 regulates the expression of antioxidant genes through Nrf2/KEAP1/ARE pathway, thus alleviating oxidative stress in DN (Tanase et al., 2022)
